Patients infected with H. pylory and ulcers must have an antibiotic course in order to eradicate infection. Long term treatment with proton pump inhibitors (i.e omeprazole) or other antisecretory drugs is only recommended in patients who cannot stop treatment with aspirin or antiinflammatory drugs. When there are no visible lesions in the stomach secondary to H. pylori infection, it is not clear whether it is necessary or not to look for H. pylori and to treat it, since the results of scientific studies are contradictory. Some experts, however, recommend “look and treat” strategy in all patients with symptoms suspected to be related to H. pylori infection. Nevertheless, the doctor will choose the best strategy to diagnose and to treat (if necessary) in each patient.
It is not easy to treat the H. pylori infection, since the stomach is not an hospitalary place for the cells to defeat H. pylori. For this, it is necessary to associate several antiacid drugs with antibiotics to manage the infection. The first option compresses three different medicines (two antibiotics and a proton pump inhibitor) for 7 to 10 days. Before starting treatment, the doctor will make sure that the patient is not allergic to any of the drugs prescribed.
The initial efficacy of the eradication therapy is aproximately 7-8 of every 10 patients. In patients who fail to eradicate infection at a first attemp, it is possible to give a second course of drugs (different from the previous ones).